PFF’s Top NFL Week 5 Bets You’ll Want to Jump On

On Oct 6, 2025

PFF Bets of the Week: NFL Week 5

Week 5 is here, and the PFF crew is back with their favorite bets of the week — powered by the ever-reliable PFF Player Prop Tool.

This tool gives real-time projections, matchup stats, and the best odds in one neat package. It’s the same kind of advanced data that all 32 NFL teams use — just now it’s open to bettors too.

Let’s dive into what the PFF analysts are locking in for this week. For the record, their collective record so far sits at 10-13-1 on the year. Not bad, but plenty of room to heat up.

Trevor Sikkema (2-2)

Pick: Kenneth Walker III (Seattle Seahawks) – Over 1.5 Receptions (-135, BetMGM)

Walker’s been a bit quiet in the passing game this year, snagging just one catch in each of his last three outings. Still, he smashed this same mark in 11 games last season. His 74.9 PFF receiving grade is actually second-best on the team this season.

Now, he’s up against a Buccaneers defense that’s been getting picked apart by running backs through the air. This feels like the perfect bounce-back spot for Walker’s receiving volume.

Dalton Wasserman (3-1)

Pick: Cam Skattebo (New York Giants) – Over 2.5 Receptions (+106, FanDuel)

Skattebo slowly turned into the main guy in the Giants’ backfield. With Malik Nabers done for the season and Tyrone Tracy likely out again, the offense is desperate for options.

The Saints’ defense hasn’t done well against running backs catching passes — allowing an insane 94.4% completion rate to RB targets (third-worst in the league).

Expect coach Brian Daboll to scheme up some creative passing plays that get Skattebo plenty of touches.

Ben Linsey (3-1)

Pick: James Cook (Buffalo Bills) – Under 80.5 Rush Yards (-115, BetMGM)

Cook’s been running wild lately with three straight 100-yard games, but this week’s matchup vs. New England isn’t the same cakewalk. The Patriots’ defense ranks fourth in fewest rush yards allowed to RBs this season.

Their defensive mindset under Mike Vrabel is still all about stopping the run — a trademark from his Titans days. With the line creeping higher each week, Linsey’s leaning toward the under here.

Mason Cameron (0-3-1)

Pick: Jake Browning (Cincinnati Bengals) – Under 225.5 Passing Yards (-115, BetMGM)

Browning just can’t catch a break behind that shaky offensive line. He’s thrown for under 150 yards in both starts this season, and his numbers under pressure are brutal — 25.8 passer rating, dead last among 38 QBs, and just 3.9 yards per attempt.

Even though Detroit doesn’t bring insane pressure, Aidan Hutchinson is coming off a hot streak and will face Amarius Mims, who’s been inconsistent. Browning could be in for another rough afternoon.

Max Chadwick (2-2)

Pick: Jake Ferguson (Dallas Cowboys) – Over 4.5 Receptions (-188, FanDuel)

Ferguson’s been money all year, hitting this number in every game so far. Over the last three games, he’s averaging nearly 10 catches per contest!

He leads all tight ends in targets (39) and receptions (34), which is 10 more than the next closest player. And now he gets a Jets defense that gives up the second-most targets to tight ends in the league. The streak should keep rolling.

Gordon McGuinness (0-4)

Pick: Brock Bowers (Las Vegas Raiders) – Under 5.5 Receptions (-148, Caesars)

Bowers hasn’t gone over this number once this season, and guess what — no tight end has hit six catches against the Colts yet.

He’s been Geno Smith’s go-to when under pressure, but Smith’s been shaky in those situations, with just a 35.5 passing grade (29th out of 33 QBs). With the Colts’ tight coverage and pressure, Bowers might once again fall short of this mark.

Players to Watch

Kenneth Walker III – Could surprise as a short-yardage receiver.
Cam Skattebo – Emerging dual-threat for the Giants.
Jake Ferguson Continues to dominate the TE receptions leaderboard.

Betting Tips

If you’re tailing these plays, shop around for the best odds across BetMGM, FanDuel, and Caesars. Lines move fast, and small differences can make a big impact on long-term profits.

Also, consider correlation bets — like pairing Ferguson’s over with Dak Prescott passing overs — to maximize your returns on related outcomes.

Wrap-Up

Week 5 has plenty of betting value if you know where to look. From Walker’s sneaky receiving line to Cook’s tough matchup, these picks mix stats, form, and logic.

Let’s see if PFF’s crew can turn up the heat and improve their record this week. Either way, there’s solid data behind every play — and that’s something casual bettors can learn from.